A biology problem by anantam mudgal

Biology Level pending

According to the current concept of Central Dogma of molecular biology, information transfer from proteins to nucleic acids does not occur. Which of the following could be considered a violation of the Central Dogma? I. Synthesis of DNA on an RNA template by reverse transcriptase. II. Gene transcription being activated by a protein binding to regulatory sequences. III. Editing of RNA transcripts by the insertion and deletion of ribonucleotides. IV. A polynucleotide polymerase specifically synthesizing a gene encoding itself from free deoxyribonucleotides.

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