It's only another flesh wound Part 2

Logic Level 3

     \large \square\square \ - \ \square\square \ - \ \square\square

You are given that the numbers 1,2,3,4,5,61,2,3,4,5,6 are to be filled in the square boxes as shown above (without repetition) such that it represents a 2 digit integer subtracting two 2-digit integers.

Of all 6!=7206!=720 possible arrangements, find the largest negative resultant number.

Details and Assumptions

As an explicit example, we can have 163452=7016 - 34 - 52 = -70 and 125364=10512-53-64=-105 as a resultant number. We will choose the formal answer of 70-70 because 105<70-105<-70.

See Part 1.

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